MAP2K5 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Synonyms: MEK5, MAPKK5, PRKMK5, HsT17454

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human MAP2K5

Gene Symbol: MAP2K5

Gene ID: 5607

Swiss prot: Q13163

Calculated MW: 50kDa

Recommended dilution:
IHC:1:25-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.