MAP3K1 Polyclonal Antibody

Background:
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus.

Research Area: Cancer, Signal Transduction

Synonyms:
MAP3K1, MAPKKK1, MEKK, MEKK 1, MEKK1, SRXY6

Immunogen: A synthetic peptide of human MAP3K1 (NP_005912.1).

Swissprot: Q13233
Gene ID: 4214

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.