MAP3K11 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. 

Synonyms: MLK3, PTK1, SPRK, MLK-3, MEKK11

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human MAP3K11

Gene Symbol: MAP3K11

Gene ID: 4296

Swiss prot: Q16584

Calculated MW: 93 kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.