MAP3K13 (LZK) polyclonal (C-term), anti-human

MAP3K13 (LZK) polyclonal (C-term), anti-human

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In stock
SKU
AC-AP8008a
Catalog Number: AC-AP8008a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0977-0978
Applications: IHC-P
Datasheet

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Background:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.

Other Names:
Mitogen-activated protein kinase kinase kinase 13, Leucine zipper-bearing kinase, Mixed lineage kinase, MLK, MAP3K13 (HGNC:6852)

Target/Specificity:
This MAP3K13 (LZK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340~369 amino acids from the C-terminal region of human LZK.

Antigen Region:
340-369

Antigen Type: Synthetic Peptide

Gene Name: MAP3K13 (HGNC:6852)
Gene ID: 9175
Primary Accession: O43283
NCBI Accession: NP_001229243.1;NP_001229246.1;NP_004712.1
Other Accession: A7MBB4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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