MAP4K2 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Research Area: Cancer, Signal Transduction

Synonyms:
B lymphocyte serine/threonine protein kinase, B lymphocyte serine/threonine-protein kinase, BL44, GC kinase, GCK, Germinal center kinase, germinal centre kinase (GC kinase), M4K2, Map4k2, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, MEKKK 2, Mitogen activated protein kinase kinase kinase kinase 2, Mitogen-activated protein kinase kinase kinase kinase 2, Rab8 interacting protein, Rab8 interacting protein, formerly, Rab8-interacting protein, RAB8IP, RAB8IP, formerly

Immunogen: Recombinant protein of human MAP4K2

Swissprot: Q12851
Gene Accession: BC047865

Calculated MW: 92 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6161