MAP4K3 Polyclonal Antibody

Background:
This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.

Research Area: Signal Transduction

Synonyms:
GLK, MEKKK3, MEKKK 3, MAPKKKK3, RAB8IPL1

Immunogen: Recombinant protein of human MAP4K3

Swissprot: Q8IVH8
Gene Accession: BC071579

Calculated MW: 101 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-7257/sc-7256