MAPE polyclonal (C-term), anti-human
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In stock
SKU
AC-AP6720b
Catalog Number: AC-AP6720b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18763
Applications: IHC-P, WB, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18763
Applications: IHC-P, WB, FC
Datasheet
Request Information
Background:
MAPE is an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, its gene is also expressed in acute leukemias.
Other Names:
Melanoma antigen preferentially expressed in tumors, Opa-interacting protein 4, OIP-4, Preferentially expressed antigen of melanoma, PRAME, MAPE, OIP4
Target/Specificity:
This MAPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human MAPE.
Antigen Region:
476-502
Antigen Type: Synthetic Peptide
Gene Name: PRAME {ECO:0000303|PubMed:9047241, ECO:0000312|HGNC:HGNC:9336}
Gene ID: 23532
Primary Accession: P78395
NCBI Accession: NP_006106.1;NP_996836.1;NP_996837.1;NP_996838.1;NP_996839.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
MAPE is an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, its gene is also expressed in acute leukemias.
Other Names:
Melanoma antigen preferentially expressed in tumors, Opa-interacting protein 4, OIP-4, Preferentially expressed antigen of melanoma, PRAME, MAPE, OIP4
Target/Specificity:
This MAPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human MAPE.
Antigen Region:
476-502
Antigen Type: Synthetic Peptide
Gene Name: PRAME {ECO:0000303|PubMed:9047241, ECO:0000312|HGNC:HGNC:9336}
Gene ID: 23532
Primary Accession: P78395
NCBI Accession: NP_006106.1;NP_996836.1;NP_996837.1;NP_996838.1;NP_996839.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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