MAPK11 (clone 4H6H6), anti-human
€539.00
In stock
SKU
252738
Protein Family: Enzymes, Protein Kinases
Pathway and Disease: Cancers, Signaling Molecules and Interaction
Description:
MAPK11 (Mitogen-activated protein kinase 11) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is most closely related to p38 MAP kinase, both of them can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
Alternate Names: Mitogen-activated protein kinase 11, MAP kinase 11, MAPK 11, Mitogen-activated protein kinase p38 beta, MAP kinase p38 beta, p38b, Stress-activated protein kinase 2b, SAPK2b, p38-2, l PRKM11, SAPK2, SAPK2B,
Application Notes: WB: 1:500-1:2000
Accession No.: Q15759
Antigen: Purified recombinant fragment of MAPK11 (aa251-363) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Signaling Molecules and Interaction
Description:
MAPK11 (Mitogen-activated protein kinase 11) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is most closely related to p38 MAP kinase, both of them can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
Alternate Names: Mitogen-activated protein kinase 11, MAP kinase 11, MAPK 11, Mitogen-activated protein kinase p38 beta, MAP kinase p38 beta, p38b, Stress-activated protein kinase 2b, SAPK2b, p38-2, l PRKM11, SAPK2, SAPK2B,
Application Notes: WB: 1:500-1:2000
Accession No.: Q15759
Antigen: Purified recombinant fragment of MAPK11 (aa251-363) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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