MAPK11 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase. [

Research Area: Signal Transduction

Synonyms:
Human p38Beta MAP kinase mRNA complete cds, MAP kinase 11, MAP kinase p38 beta, MAPK 11, Mapk11, Mitogen activated protein kinase 11, Mitogen activated protein kinase p38 2, Mitogen activated protein kinase p38 beta, Mitogen-activated protein kinase 11, Mitogen-activated protein kinase p38 beta, MK11, p38 2, p38-2, p38B, p38Beta, P38BETA2, PRKM11, Protein kinase mitogen activated 11, SAPK2, SAPK2B, Stress activated protein kinase 2, Stress activated protein kinase 2b, Stress-activated protein kinase 2

Immunogen: Synthetic peptide of human MAPK11

Swissprot: Q15759
Gene Accession: NP_002742

Calculated MW: 41 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6176/sc-15918/sc-6187