MAPK11 polyclonal (C-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP7509B
Catalog Number: AC-AP7509B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB6825
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB6825
Applications: WB
Datasheet
Request Information
Background:
P38 beta is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by changes in osmolarity of the extracellular environment, proinflammatory cytokines and cellular stress. This protein preferentially phosphorylates transcription factor ATF2. It is activated by phosphorylation on threonine and tyrosine by MKK6, and inhibited by pyridinyl-imidazole related compounds. Highest levels of expression are found in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
Other Names:
Mitogen-activated protein kinase 11, MAP kinase 11, MAPK 11, Mitogen-activated protein kinase p38 beta, MAP kinase p38 beta, p38b, Stress-activated protein kinase 2b, SAPK2b, p38-2, MAPK11, PRKM11, SAPK2, SAPK2B
Target/Specificity:
This MAPK11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-359 amino acids from the C-terminal region of human MAPK11.
Antigen Region:
334-359
Antigen Type: Synthetic Peptide
Gene Name: MAPK11
Gene ID: 5600
Primary Accession: Q15759
NCBI Accession: NP_002742.3
Other Accession: Q2XNF2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
P38 beta is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by changes in osmolarity of the extracellular environment, proinflammatory cytokines and cellular stress. This protein preferentially phosphorylates transcription factor ATF2. It is activated by phosphorylation on threonine and tyrosine by MKK6, and inhibited by pyridinyl-imidazole related compounds. Highest levels of expression are found in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
Other Names:
Mitogen-activated protein kinase 11, MAP kinase 11, MAPK 11, Mitogen-activated protein kinase p38 beta, MAP kinase p38 beta, p38b, Stress-activated protein kinase 2b, SAPK2b, p38-2, MAPK11, PRKM11, SAPK2, SAPK2B
Target/Specificity:
This MAPK11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-359 amino acids from the C-terminal region of human MAPK11.
Antigen Region:
334-359
Antigen Type: Synthetic Peptide
Gene Name: MAPK11
Gene ID: 5600
Primary Accession: Q15759
NCBI Accession: NP_002742.3
Other Accession: Q2XNF2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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