MAPK13 polyclonal, anti-human, mouse, rat

Background:
Lipopolysaccharide has been shown to induce tyrosine phosphorylation of a unique protein, which is designated p38. p38 is a member of the MAP kinase family with features most closely resembling those of the Saccharo-myces cerevisiae protein Hog1. p38 and Hog1 share a TGY phosphorylation sequence, whereas most other MAP kinase family proteins have a TEY sequence. A related protein, p38b, has been shown to phosphorylate ATF-2 at a 20-fold higher rate than p38, suggesting distinct substrate preferences. Stress activated protein kinase-4, or SAPK4, also designated p38d, is a related protein that is phosphorylated by MKK6 in response to cytokines and cellular stresses.

Alternative Name:
Mitogen-activated protein kinase 13, MAP kinase 13, MAPK 13, Mitogen-activated protein kinase p38 delta, MAP kinase p38 delta, Stress-activated protein kinase 4, MAPK13, PRKM13, SAPK4

Application Dilution: WB: 1:500~1:1000

Specificity: MAPK13 polyclonal antibody detects endogenous levels of MAPK13 protein.

Immunogen:
A synthetic peptide corresponding to residues in Human MAPK13

MW: ~ 42 kDa

Swis Prot.: O15264

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.