MAPK14 polyclonal (T179), anti-human
€0.00
In stock
SKU
AC-AP7226e
Catalog Number: AC-AP7226e
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12734
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12734
Applications: WB
Datasheet
Request Information
Background:
MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Other Names:
Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Stress-activated protein kinase 2a, SAPK2a, MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A
Target/Specificity:
This MAPK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from human MAPK14.
Antigen Region:
158-187
Antigen Type: Synthetic Peptide
Gene Name: MAPK14 (HGNC:6876)
Gene ID: 1432
Primary Accession: Q16539
NCBI Accession: NP_001306.1;NP_620581.1;NP_620582.1;NP_620583.1
Other Accession: P70618; P47811; Q9DGE2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Other Names:
Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Stress-activated protein kinase 2a, SAPK2a, MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A
Target/Specificity:
This MAPK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from human MAPK14.
Antigen Region:
158-187
Antigen Type: Synthetic Peptide
Gene Name: MAPK14 (HGNC:6876)
Gene ID: 1432
Primary Accession: Q16539
NCBI Accession: NP_001306.1;NP_620581.1;NP_620582.1;NP_620583.1
Other Accession: P70618; P47811; Q9DGE2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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