MAPKAPK-2 (phospho Thr222) Polyclonal Antibody

Background:
mitogen-activated protein kinase-activated protein kinase 2(MAPKAPK2) Homo sapiens This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Alternative Names:
MAPKAPK2, MAP kinase-activated protein kinase 2, MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAP-K2, MAPKAPK-2, MK-2, MK2

Immunogen: The antiserum was produced against synthesized peptide derived from human MAPKAPK-2 around the phosphorylation site of Thr222. AA range:188-237

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 45

GeneID: MAPKAPK2

Storage: -20°C/1 year

NOTE: For Research Use Only