MAPKAPK3 antibody (clone 4B11), anti-human
€435.00
In stock
SKU
AC-AT2797a
Catalog Number: AC-AT2797a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB
Request Information AC-AT2797a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB
Request Information AC-AT2797a">Request Information
Background:
This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
Other Names:
MAP kinase-activated protein kinase 3, MAPK-activated protein kinase 3, MAPKAP kinase 3, MAPKAP-K3, MAPKAPK-3, MK-3, Chromosome 3p kinase, 3pK, MAPKAPK3
Antigen Type:
Recombinant Protein
Gene Name: MAPKAPK3
Gene ID: 7867
NCBI Accession: NP_001230854.1;NP_001230855.1;NP_004626.1
Primary Accession: Q16644
Other Accession: NM_004635
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
Other Names:
MAP kinase-activated protein kinase 3, MAPK-activated protein kinase 3, MAPKAP kinase 3, MAPKAP-K3, MAPKAPK-3, MK-3, Chromosome 3p kinase, 3pK, MAPKAPK3
Antigen Type:
Recombinant Protein
Gene Name: MAPKAPK3
Gene ID: 7867
NCBI Accession: NP_001230854.1;NP_001230855.1;NP_004626.1
Primary Accession: Q16644
Other Accession: NM_004635
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review