MAPKK2 polyclonal, anti-human, mouse, rat

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Cancers, Signal Transduction, Immune System, Cell Communication, Cell Motility, Nervous and Sensory Systems, Endocrine System

Description:
MAPKK2 (Dual specificity mitogen-activated protein kinase kinase 2) belongs to Ser/Thr protein kinase, MAP kinase subfamily. It catalyzes the concomitant phosphorylation of threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MAPKK2 activates the ERK1 and ERK2 MAP kinases. It is itself dependent on Ser/Thr phosphorylation for activity catalyzed by MAP kinases (RAF or MEKK1).

Alternate Names: MAPKK2, Dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, ERK activator kinase 2, MAPK/ERK kinase 2, MEK2, MAP2K2, MKK2, PRKMK2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P36507

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MAPKK2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.