MAPKK3 (MEK3) polyclonal, anti-human, mouse, rat

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Signaling Molecules and Interaction, Immune System, Endocrine System, Infectious Diseases, Neurodegenerative Disorders

Description:
Dual specificity mitogen-activated protein kinase kinase 3 (MAPPK3, MEK3) is a dual specificity kinase. MAPPK3 is activated by cytokines and environmental stress in vivo. MAPKK3 catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue on MAP kinase p38. Defects in MAPKK3 have been involved in colon cancer.

Alternate Names: Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAPKK3, MAPK/ERK kinase 3, MEK 3, MAP2K3, MEK3, MKK3, PRKMK3

Application Notes: E: 1:10,000-1:50,000; WB: 1:200-1:1,000; IHC: 1:200-1:500

Accession No.: P46734

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MAPKK3(MEK3).

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.