MARC1 Polyclonal Antibody

Background:
MOSC1 (MOCO sulphurase C-terminal domain containing 1), also known as MARC1, is a 337 amino acid mitochondrial protein that is thought to function as an oxidoreductase. Existing as three alternatively spliced isoforms, MOSC1 contains one MOSC domain and binds molybdenum as a cofactor. The gene encoding MOSC1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3, 000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Research Area: Metabolism, Signal Transduction

Synonyms:
FLJ22390, MARC1, Mitochondrial amidoxime reducing component 1, MOCO sulphurase C terminal domain containing 1, MOSC 1, MOSC domain containing protein 1 mitochondrial

Immunogen: Synthetic peptide of human MARC1

Swissprot: Q5VT66
Gene Accession: NP_073583

Calculated MW: 37 kDa
Observed MW: Refer to figures

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1.2 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-243510