MARCH11 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13811b
Background:
MARCH11 is a member of the MARCH family of membrane-boundE3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin(see MIM 191339) to target lysines in substrate proteins, therebysignaling their intracellular transport. March11 appears to have arole in ubiquitin-mediated protein sorting in the trans-Golginetwork (TGN)-multivesicular body (MVB) transport pathway (Morokumaet al., 2007 [PubMed 17604280]).
Other Names:
E3 ubiquitin-protein ligase MARCH11, 632-, Membrane-associated RING finger protein 11, Membrane-associated RING-CH protein XI, MARCH-XI, MARCH11
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13811b was selected from the C-term region of MARCH11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MARCHF11 (HGNC:33609)
Gene ID: 441061
Primary Accession: A6NNE9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
MARCH11 is a member of the MARCH family of membrane-boundE3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin(see MIM 191339) to target lysines in substrate proteins, therebysignaling their intracellular transport. March11 appears to have arole in ubiquitin-mediated protein sorting in the trans-Golginetwork (TGN)-multivesicular body (MVB) transport pathway (Morokumaet al., 2007 [PubMed 17604280]).
Other Names:
E3 ubiquitin-protein ligase MARCH11, 632-, Membrane-associated RING finger protein 11, Membrane-associated RING-CH protein XI, MARCH-XI, MARCH11
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13811b was selected from the C-term region of MARCH11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MARCHF11 (HGNC:33609)
Gene ID: 441061
Primary Accession: A6NNE9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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