MARCH8 polyclonal, anti-mouse, rat

Background:
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).

Synonyms: CMIR, MARCH-VIII, MIR, RNF178, c-MIR

Cellular Location: Cytoplasmic vesicle membrane Early endosome membrane Lysosome membrane Multi-pass membrane protein

Immunogen:
Recombinant protein of human 42802

Gene Symbol: 43167

Gene ID: 220972

Swiss prot: Q5T0T0

Calculated MW: 33kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.