MARCH9 polyclonal, anti-human, mouse, rat

Background:
MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]).

Synonyms: MARCH-IX, RNF179

Cellular Location: Golgi apparatus membrane Lysosome membrane Multi-pass membrane protein

Immunogen:
Recombinant protein of human MARCH9

Gene Symbol: 43168

Gene ID: 92979

Swiss prot: Q86YJ5

Calculated MW: 38kDa

Recommended dilution:
WB 1:1000-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.