MARCKS (Phospho-Ser159/163) Rabbit polyclonal antibody, anti-human, mouse, rat

MARCKS (Phospho-Ser159/163) Rabbit polyclonal antibody, anti-human, mouse, rat

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In stock
SKU
BT-AP11241
Catalog Number: BT-AP11241
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Application(s): WB
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Background:
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane| leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility| phagocytosis| membrane trafficking and mitogenesis.

Research Area: Cardiovascular, Signal transduction

Synonyms: MARCKS , Ser159/163 , Myristoylated alanine-rich C-kinase substrate, MARCKS, Protein kinase C substrate, 80 kDa protein, light chain, 80K-L protein, PKCSL

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year
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