MARCKS polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Synonyms: 80K-L, MACS, PKCSL, PRKCSL

Cellular Location: Cytoplasm Lipid-anchor Membrane cytoskeleton

Immunogen:
A synthetic peptide of human MARCKS

Gene Symbol: MARCKS

Gene ID: 4082

Swiss prot: P29966

Calculated MW: 32kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.