MARCO polyclonal (N-term), anti-human
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In stock
SKU
AC-AP9891A
Catalog Number: AC-AP9891A
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB24662
Applications: WB, IHC-P, FC
Datasheet
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Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB24662
Applications: WB, IHC-P, FC
Datasheet
Request Information
Background:
MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
Other Names:
Macrophage receptor MARCO, Macrophage receptor with collagenous structure, Scavenger receptor class A member 2, MARCO, SCARA2
Target/Specificity:
This MARCO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids of human MARCO.
Antigen Region:
13-40
Antigen Type: Synthetic Peptide
Gene Name: MARCO
Gene ID: 8685
Primary Accession: Q9UEW3
NCBI Accession: NP_006761.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
Other Names:
Macrophage receptor MARCO, Macrophage receptor with collagenous structure, Scavenger receptor class A member 2, MARCO, SCARA2
Target/Specificity:
This MARCO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids of human MARCO.
Antigen Region:
13-40
Antigen Type: Synthetic Peptide
Gene Name: MARCO
Gene ID: 8685
Primary Accession: Q9UEW3
NCBI Accession: NP_006761.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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