MATK polyclonal (N-term), anti-human

MATK polyclonal (N-term), anti-human

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In stock
SKU
AC-AP7714A
Catalog Number: AC-AP7714A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB03166
Applications: WB
Datasheet

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Background:
MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

Other Names:
Megakaryocyte-associated tyrosine-protein kinase, CSK homologous kinase, CHK, Hematopoietic consensus tyrosine-lacking kinase, Protein kinase HYL, Tyrosine-protein kinase CTK, MATK, CTK, HYL

Target/Specificity:
This MATK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MATK.

Antigen Region:
1-30

Antigen Type: Synthetic Peptide

Gene Name: MATK
Gene ID: 4145
Primary Accession: P42679
NCBI Accession: NP_002369.2;NP_647611.1;NP_647612.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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