MATR3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8091
Background:
Matrin-3 is a nuclear matrix protein containing one matrin-type zinc finger and two RRM (RNA recognition motif) domains. Matrin-3 plays a role in transcription and may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the PSF-p54/NRB heteromer, Matrin-3 may play a role in the nuclear retention of defective RNAs. As the main substrate for PKA-mediated phosphorylation, Matrin-3 may serve as a rapid way of transferring information from synapses containing NMDA receptors to neuronal nuclei under physiological conditions. Also, the phosphorylation of Matrin-3 may contribute to neuronal death under pathological conditions. It is likely that Matrin-3 activity is regulated by calcium dependent interaction with CaM I and also by caspase induced cleavage.
Alternative Name:
Matrin-3, MATR3, KIAA0723
Application Dilution: WB: 1:500~1:2000
Specificity: MATR3 polyclonal antibody detects endogenous levels of MATR3 protein.
Immunogen:
Recombinant full length Human MATR3.
MW: ~ 95 kDa
Swis Prot.: P43243
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Matrin-3 is a nuclear matrix protein containing one matrin-type zinc finger and two RRM (RNA recognition motif) domains. Matrin-3 plays a role in transcription and may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the PSF-p54/NRB heteromer, Matrin-3 may play a role in the nuclear retention of defective RNAs. As the main substrate for PKA-mediated phosphorylation, Matrin-3 may serve as a rapid way of transferring information from synapses containing NMDA receptors to neuronal nuclei under physiological conditions. Also, the phosphorylation of Matrin-3 may contribute to neuronal death under pathological conditions. It is likely that Matrin-3 activity is regulated by calcium dependent interaction with CaM I and also by caspase induced cleavage.
Alternative Name:
Matrin-3, MATR3, KIAA0723
Application Dilution: WB: 1:500~1:2000
Specificity: MATR3 polyclonal antibody detects endogenous levels of MATR3 protein.
Immunogen:
Recombinant full length Human MATR3.
MW: ~ 95 kDa
Swis Prot.: P43243
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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