MAZ rabbit polyclonal, anti-human, mouse, rat

Backgroud: function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.,similarity:Contains 6 C2H2-type zinc fingers.,subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures.,subunit:Interacts with BPTF.,tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).,function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.,similarity:Contains 6 C2H2-type zinc fingers.,subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures.,subunit:Interacts with BPTF.,tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).,

Synonyms: MAZ, ZNF801, Myc-associated zinc finger protein, MAZI, Pur-1, Purine-binding transcription factor, Transcription factor Zif87, ZF87, Zinc finger protein 801

Gene Name: MAZ

Gene ID: 4150

SwissProt ID: P56270

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.