MBD2 polyclonal, anti-human, mouse, rat

MBD2 polyclonal, anti-human, mouse, rat

€469.00
In stock
SKU
252158
Catalog Nr.: 252158
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Datasheet
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Protein Family: Transcription Factors

Pathway and Disease: Transcription

Description:
Methyl-CpG-binding domain protein 2 (MBD2) CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. MBD2 binds hemi-methylated DNA as well. MBD2 recruits histone deacetylases and DNA methyltransferases, acts as a transcriptional repressor, and plays a role in gene silencing.

Alternate Names: Methyl-CpG-binding domain protein 2, Methyl-CpG-binding protein MBD2, Demethylase, DMTase, MBD2

Application Notes: E: 1:10,000-1:50,000; WB: 1:200-1:500

Accession No.: Q9UBB5

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MBD2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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