MBP Polyclonal Antibody

Background:
MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. MBP has six isoforms. Catalog#10458-1-AP is capable of recognizing multiple isoforms of MBP.

Research Area: Cancer, Neuroscience, Tags and Cell Markers

Synonyms:
GDB, Golli MBP, Golli MBP, myelin basic protein, Hemopoietic MBP, HMBPR, HUGO, MBP, MBP_CAVPO, MBP, MGC99675, MLD, Myelin A1 protein, Myelin A1 Protein, basic, Myelin basic protein, Myelin Deficient, Myelin membrane encephalitogenic protein, OTTHUMP00000163776, OTTHUMP00000174387, OTTHUMP00000174388, SHI, Shiverer, SP

Immunogen: Recombinant protein corresponding to Mouse Myelin Basic Protein

Swissprot: P04370,P02688

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 100 μg/mL
Dilution: IHC 1:300-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.