MBTPS2 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP12972a
Catalog Number: AC-AP12972a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32439
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32439
Applications: IHC-P, WB
Datasheet
Request Information
Background:
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.
Other Names:
Membrane-bound transcription factor site-2 protease, Endopeptidase S2P, Sterol regulatory element-binding proteins intramembrane protease, SREBPs intramembrane protease, MBTPS2, S2P
Target/Specificity:
This MBTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human MBTPS2.
Antigen Region:
15-44
Antigen Type: Synthetic Peptide
Gene Name: MBTPS2 {ECO:0000303|PubMed:19361614, ECO:0000312|HGNC:HGNC:15455}
Gene ID: 51360
Primary Accession: O43462
NCBI Accession: NP_056968.1
Other Accession: Q8CHX6; Q0III2; NP_056968.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.
Other Names:
Membrane-bound transcription factor site-2 protease, Endopeptidase S2P, Sterol regulatory element-binding proteins intramembrane protease, SREBPs intramembrane protease, MBTPS2, S2P
Target/Specificity:
This MBTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human MBTPS2.
Antigen Region:
15-44
Antigen Type: Synthetic Peptide
Gene Name: MBTPS2 {ECO:0000303|PubMed:19361614, ECO:0000312|HGNC:HGNC:15455}
Gene ID: 51360
Primary Accession: O43462
NCBI Accession: NP_056968.1
Other Accession: Q8CHX6; Q0III2; NP_056968.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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