MC3R polyclonal, anti-mouse, rat
€388.00
In stock
SKU
BS7740
Background:
The melanocortin family comprises the α-, β- and γ- melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.
Alternative Name:
BMIQ9, MC3, MC3 R, MC3-R, Mc3r, MC3R_HUMAN, melanocortin 3 receptor, Melanocortin receptor 3, OB20, Obesity quantitative trait locus, OQTL,
Application Dilution: WB: 1:500~1:2000
Specificity: MC3R polyclonal antibody detects endogenous levels of MC3R protein.
Immunogen:
Recombinant full length Human MC3R.
MW: ~ 55 kDa
Swis Prot.: P41968
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The melanocortin family comprises the α-, β- and γ- melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.
Alternative Name:
BMIQ9, MC3, MC3 R, MC3-R, Mc3r, MC3R_HUMAN, melanocortin 3 receptor, Melanocortin receptor 3, OB20, Obesity quantitative trait locus, OQTL,
Application Dilution: WB: 1:500~1:2000
Specificity: MC3R polyclonal antibody detects endogenous levels of MC3R protein.
Immunogen:
Recombinant full length Human MC3R.
MW: ~ 55 kDa
Swis Prot.: P41968
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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