MCA1 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP6721b
Catalog Number: AC-AP6721b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18767
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18767
Applications: IHC-P, WB
Datasheet
Request Information
Background:
MCA1 is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.
Other Names:
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43, Endothelial monocyte-activating polypeptide 2, EMAP-2, Endothelial monocyte-activating polypeptide II, EMAP-II, Small inducible cytokine subfamily E member 1, AIMP1, EMAP2, SCYE1
Target/Specificity:
This MCA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-268 amino acids from the C-terminal region of human MCA1.
Antigen Region:
242-268
Antigen Type: Synthetic Peptide
Gene Name: AIMP1
Gene ID: 9255
Primary Accession: Q12904
NCBI Accession: NP_001135887.1;NP_001135888.1;NP_004748.2
Other Accession: P31230; O54873
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
MCA1 is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.
Other Names:
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43, Endothelial monocyte-activating polypeptide 2, EMAP-2, Endothelial monocyte-activating polypeptide II, EMAP-II, Small inducible cytokine subfamily E member 1, AIMP1, EMAP2, SCYE1
Target/Specificity:
This MCA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-268 amino acids from the C-terminal region of human MCA1.
Antigen Region:
242-268
Antigen Type: Synthetic Peptide
Gene Name: AIMP1
Gene ID: 9255
Primary Accession: Q12904
NCBI Accession: NP_001135887.1;NP_001135888.1;NP_004748.2
Other Accession: P31230; O54873
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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