MCCC1 Polyclonal Antibody

Background:
This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Research Area: Metabolism, Signal transduction

Synonyms:
3-methylcrotonyl-CoA carboxylase 1, 3-methylcrotonyl-CoA carboxylase biotin-containing subunit, 3-methylcrotonyl-CoA carboxylase, alpha, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha, DKFZp686B20267, FLJ25545, MCC-B, MCCA, MCCase subunit alpha, methylcrotonoyl-CoA carboxylase 1 (alpha), methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial, methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)

Immunogen: Fusion protein of human MCCC1

Swissprot: Q96RQ3
Gene Accession: BC004187

Calculated MW: 80 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.78 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.