MCCC2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Alternative Name:
MCCB,

Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Specificity: MCCC2 polyclonal antibody detects endogenous levels of MCCC2 protein.

Immunogen:
Recombinant protein of human MCCC2.

MW: ~ 61 kDa

Swis Prot.: Q9HCC0

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.