MCF2L polyclonal (C-term), anti-human
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In stock
SKU
AC-AP18793B
Catalog Number: AC-AP18793B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB38890
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB38890
Applications: WB
Datasheet
Request Information
Background:
Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.
Other Names:
Guanine nucleotide exchange factor DBS, DBL's big sister, MCF2-transforming sequence-like protein, MCF2L, KIAA0362
Target/Specificity:
This MCF2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1049-1075 amino acids from the C-terminal region of human MCF2L.
Antigen Region:
1049-1075
Antigen Type: Synthetic Peptide
Gene Name: MCF2L
Gene ID: 23263
Primary Accession: O15068
NCBI Accession: NP_001106203.2;NP_079255.4
Other Accession: NP_001106203.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.
Other Names:
Guanine nucleotide exchange factor DBS, DBL's big sister, MCF2-transforming sequence-like protein, MCF2L, KIAA0362
Target/Specificity:
This MCF2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1049-1075 amino acids from the C-terminal region of human MCF2L.
Antigen Region:
1049-1075
Antigen Type: Synthetic Peptide
Gene Name: MCF2L
Gene ID: 23263
Primary Accession: O15068
NCBI Accession: NP_001106203.2;NP_079255.4
Other Accession: NP_001106203.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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