MCFD2 polyclonal, anti-human, rat
€305.00
In stock
SKU
BS60509
Background:
Multiple coagulation factor deficiency protein 2 (MCFD2) is localized in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) through a direct, calcium-dependent interaction with LMAN1. The MCFD2-LMAN1 complex forms a specific cargo receptor for the transport of selected proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in the MCFD2 gene may cause of factor V and factor VIII combined deficiency (F5F8D). F5F8D is an autosomal recessive human bleeding disorder characterized by the reduction of both clotting proteins.
Alternative Name:
Multiple coagulation factor deficiency protein 2, Neural stem cell-derived neuronal survival protein, MCFD2, SDNSF
Application Dilution: WB: 1:500~1:1000
Specificity: MCFD2 polyclonal antibody detects endogenous levels of MCFD2 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human MCFD2.
MW: ~ 16 kDa
Swis Prot.: Q8NI22
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Multiple coagulation factor deficiency protein 2 (MCFD2) is localized in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) through a direct, calcium-dependent interaction with LMAN1. The MCFD2-LMAN1 complex forms a specific cargo receptor for the transport of selected proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in the MCFD2 gene may cause of factor V and factor VIII combined deficiency (F5F8D). F5F8D is an autosomal recessive human bleeding disorder characterized by the reduction of both clotting proteins.
Alternative Name:
Multiple coagulation factor deficiency protein 2, Neural stem cell-derived neuronal survival protein, MCFD2, SDNSF
Application Dilution: WB: 1:500~1:1000
Specificity: MCFD2 polyclonal antibody detects endogenous levels of MCFD2 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human MCFD2.
MW: ~ 16 kDa
Swis Prot.: Q8NI22
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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