MCL1 Antibody (Center) Blocking peptide

Background:
This gene encodes an anti-apoptotic protein, which is amember of the Bcl-2 family. Alternative splicing results inmultiple transcript variants. The longest gene product (isoform 1)enhances cell survival by inhibiting apoptosis while thealternatively spliced shorter gene products (isoform 2 and isoform3) promote apoptosis and are death-inducing.

Other Names:
Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl2-L-3, Bcl-2-related protein EAT/mcl1, mcl1/EAT, MCL1, BCL2L3

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13704c was selected from the Center region of MCL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: MCL1

Gene ID: 4170
Primary Accession: Q07820
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.