MCL1 Polyclonal Antibody

Background:
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Research Area: Cancer, Cell Biology, Metabolism

Synonyms:
Bcl 2 related protein EAT/mcl1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, BCL2 related, Bcl2-L-3, BCL2L3, EAT, Induced myeloid leukemia cell differentiation protein Mcl 1, Induced myeloid leukemia cell differentiation protein Mcl-1, MCL 1, MCL1, MCL1-ES, mcl1/EAT, MCL1, MCL1L, MCL1S, MGC104264, MGC1839, Myeloid Cell Leukemia 1, Myeloid cell leukemia ES, Myeloid cell leukemia sequence 1, Myeloid cell leukemia sequence 1 BCL2 related, Myeloid cell leukemia sequence 1 isoform 1, OTTHUMP00000032794, OTTHUMP00000032795, TM

Immunogen: Synthesized peptide derived from the Internal region of human Mcl-1

Swissprot: Q07820

Calculated MW: 37 kDa
Observed MW: 37 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-20679/sc-958/sc-819