MCL1 polyclonal (BH3 Domain Specific), anti-human, mouse, rat
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In stock
SKU
AC-AP1312a
Catalog Number: AC-AP1312a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB00961
Applications: IHC-P, WB, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB00961
Applications: IHC-P, WB, FC
Datasheet
Request Information
Background:
The Mcl-1 protein belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
Other Names:
Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl2-L-3, Bcl-2-related protein EAT/mcl1, mcl1/EAT, MCL1, BCL2L3
Target/Specificity:
This MCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-226 amino acids from human MCL1.
Antigen Region:
191-226
Antigen Type: Synthetic Peptide
Gene Name: MCL1
Gene ID: 4170
Primary Accession: Q07820
NCBI Accession: NP_001184249.1;NP_068779.1;NP_877495.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The Mcl-1 protein belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
Other Names:
Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl2-L-3, Bcl-2-related protein EAT/mcl1, mcl1/EAT, MCL1, BCL2L3
Target/Specificity:
This MCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-226 amino acids from human MCL1.
Antigen Region:
191-226
Antigen Type: Synthetic Peptide
Gene Name: MCL1
Gene ID: 4170
Primary Accession: Q07820
NCBI Accession: NP_001184249.1;NP_068779.1;NP_877495.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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