MCM2 antibody (clone 6A8), anti-human
€435.00
In stock
SKU
AC-AT2818a
Catalog Number: AC-AT2818a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, IP, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, IP, E
Request Information AC-AT2818a">Request Information
Background:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Other Names:
DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog, Nuclear protein BM28, MCM2, BM28, CCNL1, CDCL1, KIAA0030
Antigen Type:
Recombinant Protein
Gene Name: MCM2 (HGNC:6944)
Gene ID: 4171
NCBI Accession: NP_004517.2
Primary Accession: P49736
Other Accession: BC007670
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Other Names:
DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog, Nuclear protein BM28, MCM2, BM28, CCNL1, CDCL1, KIAA0030
Antigen Type:
Recombinant Protein
Gene Name: MCM2 (HGNC:6944)
Gene ID: 4171
NCBI Accession: NP_004517.2
Primary Accession: P49736
Other Accession: BC007670
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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