MCM2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
MCM2(MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 2),also known as MITOTIN, CDCL1 or BM28, is a human nuclear protein that plays an important role in 2 crucial steps of the cell cycle, namely, onset of DNA replication and cell division. And it is similar to members of the family of early S-phase proteins. The MCM2 gene is mapped to 3q21.3. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex(pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. In the G0 stage, the MCM2 and MCM5 proteins were much less abundant than the MCM7 and MCM3 proteins, which suggests that the MCM proteins are not present in stoichiometric amounts and that only a proportion of these molecules actively participate in cell cycle regulation as part of MCM complexes.

Description:
Rabbit IgG polyclonal antibody for DNA replication licensing factor MCM2 (MCM2) detection. Tested with WB, IHC-P, ICC in Human, Mouse, Rat.

Synonyms:
BM28 antibody, CCNL 1 antibody, CCNL1 antibody, CDC like 1 antibody, CDC like-1 antibody, cdc19 antibody, CDCL 1 antibody, CDCL1 antibody, Cell devision cycle like 1 antibody, Cyclin like 1 antibody, cyclin like-1 antibody, D3S3194 antibody, DNA replication licensing factor MCM2 antibody, KIAA0030 antibody, MCM 2 antibody, MCM2 antibody, MCM2 minichromosome maintenance deficient 2 mitotin antibody, MCM2 minichromosome maintenance deficient 2 mitotin(S. cerevisiae) antibody, MCM2 minichromosome maintenance deficient 2, mitotin antibody, MCM2_HUMAN antibody, MGC10606 antibody, Minichromosome maintenance complex component 2 antibody, Minichromosome maintenance deficient 2(mitotin) antibody, Minichromosome maintenance deficient 2 mitotin antibody, Minichromosome maintenance protein 2 antibody, Minichromosome maintenance protein 2 homolog antibody, Mitotin antibody, Nuclear protein BM28 antibody, OTTHUMP00000216047 antibody, OTTHUMP00000216050 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human MCM2(889-904aa NKFSHDLKRKMILQQF), different from the related rat and mouse sequences by two amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human MCM2(889-904aa NKFSHDLKRKMILQQF), different from the related rat and mouse sequences by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.