MCM3 monoclonal, anti-human, mouse, rat
€0.00
In stock
SKU
AC-AM8514b
Catalog Number: AC-AM8514b
Size: 50 µl, 200 µl
Isotype: mouse IgG1,k
Clone Name: 1593CT377.41.73
Applications: WB, FC
Datasheet
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Size: 50 µl, 200 µl
Isotype: mouse IgG1,k
Clone Name: 1593CT377.41.73
Applications: WB, FC
Datasheet
Request Information
Background:
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.
Other Names:
DNA replication licensing factor MCM3, DNA polymerase alpha holoenzyme-associated protein P1, P1-MCM3, RLF subunit beta, p102, MCM3
Target/Specificity:
This MCM3 antibody is generated from a mouse immunized with a recombinant protein of human MCM3.
Antigen Type: Recombinant Protein
Gene Name: MCM3 (HGNC:6945)
Gene ID: 4172
Primary Accession: P25205
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.
Other Names:
DNA replication licensing factor MCM3, DNA polymerase alpha holoenzyme-associated protein P1, P1-MCM3, RLF subunit beta, p102, MCM3
Target/Specificity:
This MCM3 antibody is generated from a mouse immunized with a recombinant protein of human MCM3.
Antigen Type: Recombinant Protein
Gene Name: MCM3 (HGNC:6945)
Gene ID: 4172
Primary Accession: P25205
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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