MCM3 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
MCM3(MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 3), also called RLFB or P1 PROTEIN, is a protein that in humans is encoded by the MCM3 gene. MCM3 is one of the highly conserved mini-chromosome maintenance proteins(MCM) that are involved in the initiation of eukaryotic genome replication. The MCM3 gene is mapped to 6p12.2. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

Description:
Rabbit IgG polyclonal antibody for DNA replication licensing factor MCM3 (MCM3) detection. Tested with WB, IHC-P, ICC in Human, Mouse, Rat.

Synonyms:
Cervical cancer proto oncogene 5 antibody, DNA polymerase alpha holoenzyme associated P1 antibody, DNA polymerase alpha holoenzyme associated protein P1 antibody, DNA polymerase alpha holoenzyme-associated protein P1 antibody, DNA replication factor MCM3 antibody, DNA replication licensing factor MCM3 antibody, HCC 5 antibody, HCC5 antibody, hRlf beta subunit antibody, Human cervical cancer proto oncogene 5 antibody, MCM 3 antibody, mcm3 antibody, MCM3 minichromosome maintenance deficient 3 antibody, MCM3_HUMAN antibody, MGC1157 antibody, Minichromosome maintenance complex component 3 antibody, Minichromosome maintenance deficient 3 antibody, Minichromosome maintenance protein 3 antibody, P1 h antibody, P1 MCM3 antibody, P1 Protein antibody, P1-MCM3 antibody, P1.h antibody, p102 antibody, P102 protein antibody, Replication licensing factor beta subunit antibody, RLF beta subunit antibody, RLF subunit beta antibody, RLFB antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human MCM3(13-27aa REAQRDYLDFLDDEE), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence at the N-terminus of human MCM3(13-27aa REAQRDYLDFLDDEE), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.