MCM6 Antibody (N-term) Blocking Peptide

Background:
The protein encoded by this gene is one of the highlyconserved mini-chromosome maintenance proteins (MCM) that areessential for the initiation of eukaryotic genome replication. Thehexameric protein complex formed by the MCM proteins is a keycomponent of the pre-replication complex (pre_RC) and may beinvolved in the formation of replication forks and in therecruitment of other DNA replication related proteins. The MCMcomplex consisting of this protein and MCM2, 4 and 7 proteinspossesses DNA helicase activity, and may act as a DNA unwindingenzyme. The phosphorylation of the complex by CDC2 kinase reducesthe helicase activity, suggesting a role in the regulation of DNAreplication.

Other Names:
DNA replication licensing factor MCM6, p105MCM, MCM6

Gene Name: MCM6 (HGNC:6949)

Gene ID: 4175
Primary Accession: Q14566
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.