MCM6 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP14743a
Catalog Number: AC-AP14743a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34942
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34942
Applications: IHC-P, WB
Datasheet
Request Information
Background:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Other Names:
DNA replication licensing factor MCM6, p105MCM, MCM6
Target/Specificity:
This MCM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids from the N-terminal region of human MCM6.
Antigen Region:
80-109
Antigen Type: Synthetic Peptide
Gene Name: MCM6 (HGNC:6949)
Gene ID: 4175
Primary Accession: Q14566
NCBI Accession: NP_005906.2
Other Accession: Q2KIZ8; NP_005906.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Other Names:
DNA replication licensing factor MCM6, p105MCM, MCM6
Target/Specificity:
This MCM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids from the N-terminal region of human MCM6.
Antigen Region:
80-109
Antigen Type: Synthetic Peptide
Gene Name: MCM6 (HGNC:6949)
Gene ID: 4175
Primary Accession: Q14566
NCBI Accession: NP_005906.2
Other Accession: Q2KIZ8; NP_005906.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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