MCM7 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP16322a
Background:
The protein encoded by this gene is one of the highlyconserved mini-chromosome maintenance proteins (MCM) that areessential for the initiation of eukaryotic genome replication. Thehexameric protein complex formed by the MCM proteins is a keycomponent of the pre-replication complex (pre_RC) and may beinvolved in the formation of replication forks and in therecruitment of other DNA replication related proteins. The MCMcomplex consisting of this protein and MCM2, 4 and 6 proteinspossesses DNA helicase activity, and may act as a DNA unwindingenzyme. Cyclin D1-dependent kinase, CDK4, is found to associatewith this protein, and may regulate the binding of this proteinwith the tumorsuppressor protein RB1/RB. Alternatively splicedtranscript variants encoding distinct isoforms have been reported.
Other Names:
DNA replication licensing factor MCM7, CDC47 homolog, P11-MCM3, MCM7, CDC47, MCM2
Gene Name: MCM7 (HGNC:6950)
Gene ID: 4176
Primary Accession: P33993
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is one of the highlyconserved mini-chromosome maintenance proteins (MCM) that areessential for the initiation of eukaryotic genome replication. Thehexameric protein complex formed by the MCM proteins is a keycomponent of the pre-replication complex (pre_RC) and may beinvolved in the formation of replication forks and in therecruitment of other DNA replication related proteins. The MCMcomplex consisting of this protein and MCM2, 4 and 6 proteinspossesses DNA helicase activity, and may act as a DNA unwindingenzyme. Cyclin D1-dependent kinase, CDK4, is found to associatewith this protein, and may regulate the binding of this proteinwith the tumorsuppressor protein RB1/RB. Alternatively splicedtranscript variants encoding distinct isoforms have been reported.
Other Names:
DNA replication licensing factor MCM7, CDC47 homolog, P11-MCM3, MCM7, CDC47, MCM2
Gene Name: MCM7 (HGNC:6950)
Gene ID: 4176
Primary Accession: P33993
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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