MCM7 / CDC47 (clone SPM379), anti-human

Background:
MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.

Other Names:
CDC47; DNA replication licensing factor MCM7; MCM7 mini chromosome maintenance deficient 7; Minichromosome Maintenance 7; Mini chromosome maintenance protein 7; P1.1-MCM3; P1CDC47; P85MCM; PNAS146

Antigen Type:
Recombinant protein

Gene Name: MCM7 (HGNC:6950)
Gene ID: 4176
Primary Accession: P33993
Other Accession: 438720