MCM8 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP17408c
Catalog Number: AC-AP17408c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36786
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36786
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Other Names:
DNA helicase MCM8, Minichromosome maintenance 8, MCM8, C20orf154
Target/Specificity:
This MCM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the Central region of human MCM8.
Antigen Region:
322-350
Antigen Type: Synthetic Peptide
Gene Name: MCM8
Gene ID: 84515
Primary Accession: Q9UJA3
NCBI Accession: NP_001268449.1;NP_001268450.1;NP_001268451.1;NP_115874.3;NP_877954.1
Other Accession: NP_115874.3;NP_877954.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Other Names:
DNA helicase MCM8, Minichromosome maintenance 8, MCM8, C20orf154
Target/Specificity:
This MCM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the Central region of human MCM8.
Antigen Region:
322-350
Antigen Type: Synthetic Peptide
Gene Name: MCM8
Gene ID: 84515
Primary Accession: Q9UJA3
NCBI Accession: NP_001268449.1;NP_001268450.1;NP_001268451.1;NP_115874.3;NP_877954.1
Other Accession: NP_115874.3;NP_877954.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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