MCOLN1 Antibody (C-term) Blocking peptide

Background:
This gene encodes a memberof the transient receptorpotential (TRP) cation channel gene family. The transmembraneprotein localizes to intracellular vesicular membranes includinglysosomes, and functions in the late endocytic pathway and in theregulation of lysosomal exocytosis. The channel is permeable toCa(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changesin Ca(2+) concentration. Mutations in this gene result inmucolipidosis type IV.

Other Names:
Mucolipin-1, MG-2, Mucolipidin, MCOLN1, ML4

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13551b was selected from the C-term region of MCOLN1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: MCOLN1 {ECO:0000303|PubMed:25720963, ECO:0000312|HGNC:HGNC:13356}

Gene ID: 57192
Primary Accession: Q9GZU1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.