MCP-1 human active recombinant protein
€295.00
In stock
SKU
600148
Protein Family: Cytokines
Pathway and Disease: Cancers, Immune System, Signal Transduction, Signaling Molecules and Interaction
Alternate Names: C-C motif chemokine 2, small-inducible cytokine A2, MCP-1, monocyte chemoattractant protein-1, monocyte chemotactic protein 1, monocyte chemotactic and activating factor, MCAF, monocyte secretory protein JE, HC11, CCL2, MCP1, SCYA2Description:
Monocyte chemoattractant protein-1 (MCP-1 or C-C motif chemokine 2, CCL2) is a chemotactic factor that attracts monocytes and basophils but not neutrophilsor eosinophils. MCP-1 increases monocyte anti-tumor activity. MCP-1 is implicated int he pathogenesis of diseases characterized by monocytic infiltration such as psoriasis, rheumatoid arthritis and atherosclerosis. Recombinant Human MCP-1 produced in E. coli is a non-glycosylated polypeptide chain containing 76 amino acids with a MW of 8,607 Da.
Source: E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Applications: E, WB
Application Notes:
MCP-1 is fully biologically active when compared to standard. The specific activity as determined by the ability of MCP-1 to chemoattract human monocytes using a concentration of 4 - 15 ng/ml.
Accession No.: P13500
MW: 6807 Da
Sequence:
QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT
Purity:
Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
Pathway and Disease: Cancers, Immune System, Signal Transduction, Signaling Molecules and Interaction
Alternate Names: C-C motif chemokine 2, small-inducible cytokine A2, MCP-1, monocyte chemoattractant protein-1, monocyte chemotactic protein 1, monocyte chemotactic and activating factor, MCAF, monocyte secretory protein JE, HC11, CCL2, MCP1, SCYA2Description:
Monocyte chemoattractant protein-1 (MCP-1 or C-C motif chemokine 2, CCL2) is a chemotactic factor that attracts monocytes and basophils but not neutrophilsor eosinophils. MCP-1 increases monocyte anti-tumor activity. MCP-1 is implicated int he pathogenesis of diseases characterized by monocytic infiltration such as psoriasis, rheumatoid arthritis and atherosclerosis. Recombinant Human MCP-1 produced in E. coli is a non-glycosylated polypeptide chain containing 76 amino acids with a MW of 8,607 Da.
Source: E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Applications: E, WB
Application Notes:
MCP-1 is fully biologically active when compared to standard. The specific activity as determined by the ability of MCP-1 to chemoattract human monocytes using a concentration of 4 - 15 ng/ml.
Accession No.: P13500
MW: 6807 Da
Sequence:
QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT
Purity:
Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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