MCP antibody (clone 20000000000), anti-human
€435.00
In stock
SKU
AC-AT2822a
Catalog Number: AC-AT2822a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: E
Request Information AC-AT2822a">Request Information
Background:
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Other Names:
Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen, CD46, CD46, MCP, MIC10
Antigen Type:
Recombinant Protein
Gene Name: CD46
Gene ID: 4179
NCBI Accession: NP_002380.3;NP_722548.1;NP_758860.1;NP_758861.1;NP_758862.1;NP_758863.1;NP_758869.1;NP_758871.1
Primary Accession: P15529
Other Accession: BC030594
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Other Names:
Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen, CD46, CD46, MCP, MIC10
Antigen Type:
Recombinant Protein
Gene Name: CD46
Gene ID: 4179
NCBI Accession: NP_002380.3;NP_722548.1;NP_758860.1;NP_758861.1;NP_758862.1;NP_758863.1;NP_758869.1;NP_758871.1
Primary Accession: P15529
Other Accession: BC030594
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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